BDBM50641852 CHEMBL5572242

SMILES CN(C)C(=O)[C@H](Cc1ccc(C(F)(F)F)cc1)NC(=O)/C(C#N)=C/c1ccccc1P(C)(C)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50641852   

TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataKi:  5.40E+3nMAssay Description:Binding affinity of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) assessed as inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human Bfl-1 (1 to 151 residues) expressed in Escherichia coli BL21-Gold (DE3) using HyLite Fluor 647...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bcl-2 (unknown origin) incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mcl-1 (unknown origin) incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50641852(CHEMBL5572242)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Bcl-xl (unknown origin) incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed