BDBM50641929 CHEMBL5566228

SMILES CS(=O)(=O)C[C@H](N[C@@H](c1ccc(F)cc1)C(F)(F)F)C(=O)N[C@H](C#N)COCc1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50641929   

TargetCathepsin S(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50641929(CHEMBL5566228)
Affinity DataKi:  2.40nMAssay Description:Inhibition of recombinant Cathepsin S (unknown origin) expressed in Escherichia coli using Z-Val-Val-Arg-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCathepsin B(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50641929(CHEMBL5566228)
Affinity DataKi:  157nMAssay Description:Inhibition of human Cathepsin B using Z-Phe-Arg-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50641929(CHEMBL5566228)
Affinity DataKi:  1.95E+3nMAssay Description:Inhibition of human Cathepsin L using Z-Phe-Arg-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed