BDBM50642026 US12344595, Example 63

SMILES NS(=O)(=O)c1cccc(NC(=O)c2cc(C(F)(F)F)cnc2N2CCCC2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50642026   

TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642026(US12344595, Example 63)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642026(US12344595, Example 63)
Affinity DataIC50: 2.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent