BDBM50642133 CHEMBL5565411

SMILES O=C1NC(=O)C(Cc2ccc3nccc(-c4ccncc4)c3c2)S1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50642133   

LigandPNGBDBM50642133(CHEMBL5565411)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by kinase profiling assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642133(CHEMBL5565411)
Affinity DataIC50: 40nMAssay Description:Inhibition of AKT phosphorylation in human OVCAR-8 cells assessed as reduction in pAKT level incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed