BDBM50642162 CHEMBL5579748

SMILES O=C(Nc1cnc2ccccc2c1)c1ccc(-c2noc(C(F)(F)F)n2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50642162   

TargetHistone deacetylase 4(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandPNGBDBM50642162(CHEMBL5579748)
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of human recombinant TEV-8His-tagged HDAC4 (648 to 1057 residues) expressed in Escherichia coli (DE3) Rosetta cells using Boc-Lys-(Tfa)-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandPNGBDBM50642162(CHEMBL5579748)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC8 using Boc-Lys-(Tfa)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandPNGBDBM50642162(CHEMBL5579748)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 90...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Heinrich Heine University Dusseldorf

Curated by ChEMBL
LigandPNGBDBM50642162(CHEMBL5579748)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 90...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed