BDBM50642347 CHEMBL5572117

SMILES COc1ccc(-c2cc(OCCCCC(=O)Nc3ccccc3N)c3ncnc(C)c3c2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50642347   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Chinese Academy of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50642347(CHEMBL5572117)
Affinity DataIC50: 48nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate incubated for 1 hr in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chinese Academy of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50642347(CHEMBL5572117)
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of C-terminal 6His-FLAG-tagged human recombinant HDAC1 (1 to 482 residues) expressed in Sf9 cells using Ac-peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed