BDBM50642517 CHEMBL5592085
SMILES [O-][S+](CCN1CCCN(CC(O)Cc2ccccc2)CC1)C(c1ccc(F)cc1)c1ccc(F)cc1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50642517
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 3.52E+3nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair