BDBM50642532 CHEMBL5572067
SMILES Fc1ccc(C(SCCN2CCN(c3ccncc3)CC2)c2ccc(F)cc2)cc1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50642532
TargetSodium-dependent dopamine transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 92nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 106nMAssay Description:Displacement of [3H]WIN35428 from wild type human DAT expressed in COS-7 cells incubated for 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 136nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Human)
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institute on Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 326nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair