BDBM50642651 CHEMBL5570289

SMILES O=C1NC(=O)C(=C/C=C/c2ccc(OCc3ccc(F)cc3)cc2)C(=O)N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50642651   

TargetCathepsin B(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50642651(CHEMBL5570289)
Affinity DataIC50: 36nMAssay Description:Inhibition of cathepsin B (unknown origin) using Cbz-Phe-Arg-AMC as substrate preincubated for 5 mins followed by substrate addition by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50642651(CHEMBL5570289)
Affinity DataIC50: 40nMAssay Description:Inhibition of cathepsin L (unknown origin) using Cbz-Phe-Arg-AMC as substrate preincubated for 5 mins followed by substrate addition by fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50642651(CHEMBL5570289)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus sortase A N24 deletion mutant using Abz-LPATG-Dnp as substrate preincubated for 20 mins followed by substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50642651(CHEMBL5570289)
Affinity DataKi:  1.60E+3nMAssay Description:Covalent inhibition of Staphylococcus aureus sortase A N24 deletion mutant assessed as inactivation constant incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50642651(CHEMBL5570289)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of Staphylococcus aureus Sortase A N24 deletion mutant transpeptidation using IsdA64-323 as substrate preincubated for 20 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed