BDBM50642739 CHEMBL5575147

SMILES Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](c2cc(OCCN3CCC(O[C@H]4C[C@H](Oc5cc(N6C7CCC6CN(c6cc(-c8ccccc8O)nnc6N)C7)ccn5)C4)CC3)no2)C(C)C)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50642739   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
Arvinas LLC

Curated by ChEMBL
LigandPNGBDBM50642739(CHEMBL5575147)
Affinity DataKd:  3.40nMAssay Description:Binding affinity to VHL (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProbable global transcription activator SNF2L2(Human)
Arvinas LLC

Curated by ChEMBL
LigandPNGBDBM50642739(CHEMBL5575147)
Affinity DataKd:  72nMAssay Description:Binding affinity to his-tagged BRM bromodomain (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTranscription activator BRG1(Human)
Arvinas LLC

Curated by ChEMBL
LigandPNGBDBM50642739(CHEMBL5575147)
Affinity DataKd:  108nMAssay Description:Binding affinity to his-tagged BRG1 bromodomain (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed