BDBM50642747 CHEMBL5583756

SMILES CC(Sc1nncn1C)c1cccc(NC(=O)c2ccccc2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50642747   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642747(CHEMBL5583756)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to CBl-b (unknown origin) assessed as dissociation constant by Surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642747(CHEMBL5583756)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642747(CHEMBL5583756)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of CBL-B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642747(CHEMBL5583756)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to CBL-B (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed