BDBM50642748 CHEMBL5564717

SMILES C[C@H](Sc1nncn1C)c1cccc(NC(=O)c2ccccc2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50642748   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642748(CHEMBL5564717)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant Cbl-b by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642748(CHEMBL5564717)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CBL-B (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642748(CHEMBL5564717)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to human recombinant Cbl-b assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642748(CHEMBL5564717)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to CBL-B (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed