BDBM50642846 CHEMBL5571480

SMILES Cn1cnnc1[C@]1(c2cccc(-c3nc(C(F)(F)F)c[nH]c3=O)c2)C[C@H](C)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50642846   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50642846(CHEMBL5571480)
Affinity DataIC50: 890nMAssay Description:Inhibition of biotinylated recombinant Cbl-b (36 to 427 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) Tuner cells using a FAM-lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL(Homo sapiens)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50642846(CHEMBL5571480)
Affinity DataIC50: 6.55E+3nMAssay Description:Inhibition of cCbl (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed