BDBM50643000 CHEMBL5569248

SMILES O=C1[C@H](c2ccc(F)cc2)[C@@H](c2ccc3c(c2)OCO3)N1C1CCN(C(=O)n2nnc3ccccc32)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50643000   

TargetMonoglyceride lipase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50643000(CHEMBL5569248)
Affinity DataIC50: 0.0210nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50643000(CHEMBL5569248)
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of mouse MAGL using arachidonic acid as substrate preincubated with compound for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50643000(CHEMBL5569248)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50643000(CHEMBL5569248)
Affinity DataIC50: 0.0720nMAssay Description:Inhibition of mouse MAGL using arachidonic acid as substrate preincubated with compound for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50643000(CHEMBL5569248)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of rat MAGL expressed in human HeLa cells using 2-arachidonoylglycerol as substrate preincubated with compound for 20 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50643000(CHEMBL5569248)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFatty-acid amide hydrolase 1(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50643000(CHEMBL5569248)
Affinity DataIC50: 301nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed