BDBM50643128 CHEMBL5570405

SMILES C=CC(=O)Nc1cccc(Nc2nc(Nc3cnn(CC)c3)nc3ccc(Cl)cc23)c1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50643128   

TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50643128(CHEMBL5570405)
Affinity DataIC50: 23nMAssay Description:Inhibition of human EGFR L858R/T790M mutant (695 to 10121 residues) expressed in Sf9 cells by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50643128(CHEMBL5570405)
Affinity DataIC50: 263nMAssay Description:Inhibition of ACK1 (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed