BDBM50643169 CHEMBL5574511::US20250243196, Compound F-81

SMILES CC(C)C[C@@H](N)C(=O)Nc1ccc(-c2ccnc3[nH]ccc23)c(OC(F)(F)F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50643169   

TargetCitron Rho-interacting kinase(Human)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM50643169(CHEMBL5574511 | US20250243196, Compound F-81)
Affinity DataIC50: 36.9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetCitron Rho-interacting kinase(Human)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM50643169(CHEMBL5574511 | US20250243196, Compound F-81)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant CITK kinase domain assessed as phosphorylation of substrate ULight-ARTKQTARKSTGGKAPRICQLAGC measured after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed