BDBM50643723 CHEMBL5575710

SMILES CC(=O)N1CCc2c(c(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nn2[C@H]2CC[C@@H](CN3Cc4cc5c(cc4C3)C(=O)N(C3CCC(=O)NC3=O)C5=O)CC2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50643723   

TargetProtein cereblon(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50643723(CHEMBL5575710)
Affinity DataIC50: 2.80nMAssay Description:Binding affinity to GST-tagged human CRBN by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50643723(CHEMBL5575710)
Affinity DataIC50: 18nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCREB-binding protein(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50643723(CHEMBL5575710)
Affinity DataIC50: 19nMAssay Description:Binding affinity to CBP (unknown origin) by fluorescence Polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed