BDBM50644120 CHEMBL5566821

SMILES COc1cc([Se]C(F)(F)F)c(OC)cc1CCN

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50644120   

Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to human [125I]LSD-labeled 5-HT2A receptor expressed in HEK293 cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  6.70nMAssay Description:Binding affinity to human [125I]LSD-labeled 5-HT2C receptor expressed in HEK293 cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  10nMAssay Description:Binding affinity to human [125I]LSD-labeled 5-HT2B receptor expressed in CHO cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor (unknown origin) assessed as inhibition bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]-rauwolscine from human recombinant adrenergic alpha-2A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]-rauwolscine from human recombinant adrenergic alpha-2C receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  949nMAssay Description:Displacement of [3H]5-CT from 5-HT1B receptor (unknown origin) assessed as inhibition bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  1.05E+3nMAssay Description:Displacement of [3H]-rauwolscine from human recombinant adrenergic alpha-2B receptor expressed in human CHO-K1 cells incubated for 60 mins by spectro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]LSD from 5-HT6 receptor (unknown origin) assessed as inhibition bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Cybin IRL

Curated by ChEMBL
LigandPNGBDBM50644120(CHEMBL5566821)
Affinity DataKi:  4.92E+3nMAssay Description:Displacement of [3H]LSD from 5-HT7 receptor (unknown origin) assessed as inhibition bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed