BDBM50644132 CHEMBL5571674

SMILES Cc1cncc(NC(=O)C(=O)N2CCCCC2c2cccn2C)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50644132   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644132(CHEMBL5571674)
Affinity DataKd:  400nMAssay Description:Binding affinity to biotinylated PRMT5/MEP50 complex (unknown origin) in presence of MTA by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644132(CHEMBL5571674)
Affinity DataKi:  600nMAssay Description:Displacement of C-terminal 5'-TAMRA labeled histone H4 Me0 peptide (1 to 21) from PRMT5/MEP50 (unknown origin) incubated for 30 mins in presence of M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644132(CHEMBL5571674)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of C-terminal 5'-TAMRA labeled histone H4 Me2 peptide (1 to 21) from PRMT5/MEP50 (unknown origin) incubated for 30 mins in presence of S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644132(CHEMBL5571674)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of C-terminal 5'-TAMRA labeled histone H4 Me2 peptide (1 to 21) from PRMT5/MEP50 (unknown origin) incubated for 30 mins in presence of S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644132(CHEMBL5571674)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of C-terminal 5'-TAMRA labeled histone H4 Me0 peptide (1 to 21) from PRMT5/MEP50 (unknown origin) incubated for 30 mins in presence of M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed