BDBM50644146 CHEMBL5591896

SMILES Cc1cc(NC(=O)C(=O)N2CCCC[C@@H]2c2ccccc2)cnc1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50644146   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644146(CHEMBL5591896)
Affinity DataIC50: 60nMAssay Description:Displacement of C-terminal 5'-TAMRA labeled histone H4 Me0 peptide (1 to 21) from PRMT5/MEP50 (unknown origin) incubated for 30 mins in presence of M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644146(CHEMBL5591896)
Affinity DataIC50: 200nMAssay Description:Displacement of C-terminal 5'-TAMRA labeled histone H4 Me2 peptide (1 to 21) from PRMT5/MEP50 (unknown origin) incubated for 30 mins in presence of S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Tango Therapeutics

Curated by ChEMBL
LigandPNGBDBM50644146(CHEMBL5591896)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PRMT5 in MTAP-null human HAP1 cells incubated for 24 hrs by SDMA in-cell western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed