BDBM50644238 CHEMBL5574081

SMILES Cn1nc(C(F)(F)F)cc1-c1cc(Cl)c(Cl)c2[nH]c3c(c12)CC1(CC3)CCN(C(=O)CO)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50644238   

TargetCyclic GMP-AMP synthase(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50644238(CHEMBL5574081)
Affinity DataIC50: 5.82E+3nMAssay Description:Inhibition of cGAS in human THP1-Dual cells preincubated for 1 hr followed by cGAMP addition and measured after 24 hrs by luminescence based QUANTI-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed