BDBM50644326 CHEMBL5593916

SMILES CN1CCN(C(c2ccc(C#N)cc2)c2nnnn2Cc2ccccc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50644326   

TargetExcitatory amino acid transporter 3(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644326(CHEMBL5593916)
Affinity DataEC50:  0.200nMAssay Description:Positive allosteric modulation of EAAT3 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644326(CHEMBL5593916)
Affinity DataEC50:  1.20nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 1(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644326(CHEMBL5593916)
Affinity DataEC50:  1.60nMAssay Description:Positive allosteric modulation of EAAT1 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed