BDBM50644337 CHEMBL5567160

SMILES CN1CCN(C(c2cccnc2)c2nnnn2CCc2ccccc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50644337   

TargetExcitatory amino acid transporter 2(Rattus norvegicus)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644337(CHEMBL5567160)
Affinity DataEC50:  0.5nMAssay Description:Positive allosteric modulation of EAAT2 in Sprague-Dawley rat microglial cells assessed as increase in glutamate uptake preincubated for 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644337(CHEMBL5567160)
Affinity DataEC50:  1nMAssay Description:Positive allosteric modulation of EAAT2 (unknown origin) transfected in African green monkey COS-7 cells assessed as increase in glutamate uptake pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed