BDBM50644375 CHEMBL5563998

SMILES Nc1nc2c(ncn2[C@@H]2C[C@@H](CO)N(C(=O)CCP(=O)(O)O)C2)c(=O)[nH]1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50644375   

TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50644375(CHEMBL5563998)
Affinity DataKi:  90nMAssay Description:Inhibition of human HGPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50644375(CHEMBL5563998)
Affinity DataKi:  500nMAssay Description:Inhibition of Plasmodium falciparum HGXPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetXanthine-guanine phosphoribosyltransferase(Escherichia coli (strain K12))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50644375(CHEMBL5563998)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity to Escherichia coli XGPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50644375(CHEMBL5563998)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis HGPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed