BDBM50644400 CHEMBL5594441

SMILES O=C(Nc1ccc(-c2nc(N3CCOCC3)nc(N3CCO[C@@H](CO)C3)n2)cc1)Nc1ccc2c(c1)COC2=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50644400   

TargetSerine/threonine-protein kinase mTOR(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50644400(CHEMBL5594441)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of mTOR (unknown origin) by Lance ultra assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50644400(CHEMBL5594441)
Affinity DataIC50: 64nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50644400(CHEMBL5594441)
Affinity DataIC50: 157nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50644400(CHEMBL5594441)
Affinity DataIC50: 228nMAssay Description:Inhibition of PI3Kgamma (unknown origin) by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50644400(CHEMBL5594441)
Affinity DataIC50: 234nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed