BDBM50644416 CHEMBL5570396

SMILES CCc1oc2cccc(I)c2c1C(=O)c1cc(I)c(O)c(I)c1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50644416   

TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50644416(CHEMBL5570396)
Affinity DataKd:  120nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50644416(CHEMBL5570396)
Affinity DataEC50:  3.50E+3nMAssay Description:Binding affinity to TTR in human plasma assessed as target occupancy incubated for 6 hrs in presence of E)-S-phenyl 3-(4-hydroxy-3,5-dimethyistyryl)b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50644416(CHEMBL5570396)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of acid-induced TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by acetate buffer at pH 4.7 addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)