BDBM50644461 CHEMBL5573217

SMILES COc1c(F)cc2cc1Nc1ncc(C(F)(F)F)c(n1)NCCCCN(C)C2=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50644461   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50644461(CHEMBL5573217)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human LRRK2 G2019S mutant using [RLGRDKYKTLRQIRQ] peptide substrate by [Gamma33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50644461(CHEMBL5573217)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of wild type human LRRK2 using [RLGRDKYKTLRQIRQ] peptide substrate by [Gamma33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50644461(CHEMBL5573217)
Affinity DataIC50: 333nMAssay Description:Inhibition of NanoBRET LRRK2 (unknown origin) G2019S mutant expressed in HEK293 cells by NanoBRET TE Intracellular Kinase AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed