BDBM50644630 CHEMBL5570490

SMILES c1cc(-c2c[nH]c3cc4cnccc4cc23)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50644630   

TargetSerine/threonine-protein kinase haspin(Human)
Universite Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50644630(CHEMBL5570490)
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human Haspin kinase domain (470 to 798 residues) expressed in bacteria using histone H3 (1 to 21) peptide as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Universite Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50644630(CHEMBL5570490)
Affinity DataIC50: 479nMAssay Description:Inhibition of human recombinant PIM-1 expressed in bacteria using histone H1 as substrate incubated for 30 mins in presence of ATP by ADP-Glo kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
Universite Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50644630(CHEMBL5570490)
Affinity DataIC50: 513nMAssay Description:Inhibition of recombinant rat DYRK1A kinase domain (1 to 499 residues) expressed in bacteria using KKISGRLSPIMTEQ as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
Universite Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50644630(CHEMBL5570490)
Affinity DataIC50: 693nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate incubated for 30 mins in presence of ATP by ADP-Glo kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed