BDBM50645309 CHEMBL5562937

SMILES N=C(N)NCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CCc1ccccc1)C1CCCCC1)C(=O)c1nc2ccccc2s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50645309   

TargetTransmembrane protease serine 6(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi:  5.20nMAssay Description:Competitive tight binding inhibition of recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataIC50: 332nMAssay Description:Inhibition of human TMPRSS6 transfected in HEK293SL cells using Boc-QAR-AMC as substrate measured for 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProthrombin(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi:  395nMAssay Description:Inhibition of recombinant human thrombin using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi:  618nMAssay Description:Mixed inhibition of recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of human Matriptase transfected in HEK293SL cells using Boc-QAR-AMC as substrate measured for 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFurin(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human furin using Boc-RVRR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
Universite de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human FXA using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed