BDBM50645317 CHEMBL5571675

SMILES COc1c(F)ccc(-c2cnc3nc2NCCCNS(=O)(=O)c2cccc(c2)N3)c1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50645317   

TargetEphrin type-A receptor 4(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645317(CHEMBL5571675)
Affinity DataEC50:  190nMAssay Description:Inhibition of full length EPHA4 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in presence of K4 tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645317(CHEMBL5571675)
Affinity DataEC50:  250nMAssay Description:Inhibition of full length EPHA2 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in presence of K4 tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645317(CHEMBL5571675)
Affinity DataEC50:  470nMAssay Description:Inhibition of full length FGFR1 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in presence of K10 t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645317(CHEMBL5571675)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of full length FLT1 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in presence of K9 tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50645317(CHEMBL5571675)
Affinity DataEC50:  6.40E+3nMAssay Description:Inhibition of full length ABL1 (unknown origin) expressed in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in presence of K4 tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed