BDBM50645333 CHEMBL5564324

SMILES Cc1ccc(NC(=O)c2ccc3c(c2)c(CNCCc2ccc(-c4ccccc4)cc2)cn3C)cc1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50645333   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50645333(CHEMBL5564324)
Affinity DataIC50: 9.83E+3nMAssay Description:Inhibition of full-length N-terminal GST-tagged human CDK9 (1 to 372 residues) /His-tagged Cyclin T1 (1 to 726 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50645333(CHEMBL5564324)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of human haspin preincubated for 30 mins followed by ATP and ULight-histone H3 peptide/ULight-eIF4E binding protein addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50645333(CHEMBL5564324)
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of human CDK1/CyclinB1 preincubated for 30 mins followed by ATP and ULight-histone H3 peptide/ULight-eIF4E binding protein addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50645333(CHEMBL5564324)
Affinity DataIC50: 3.81E+4nMAssay Description:Inhibition of full-length N-terminal GST-tagged human CDK2 (1 to 298 residues) / GST-tagged CyclinA2 (1 to 432 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50645333(CHEMBL5564324)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of full-length N-terminal GST-tagged human CDK5 (1 to 292 residues) /p25 (99 to 307 residues) expressed in baculovirus expression system p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAurora kinase B(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50645333(CHEMBL5564324)
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of human wild type Aurora B preincubated for 30 mins followed by ATP and ULight-histone H3 peptide/ULight-eIF4E binding protein addition a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50645333(CHEMBL5564324)
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of full-length N-terminal GST-tagged human GSK3alpha (1 to 483 residues) expressed in baculovirus expression system preincubated for 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50645333(CHEMBL5564324)
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of full-length N-terminal GST-tagged human GSK3beta (1 to 420 residues) expressed in baculovirus expression system preincubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed