BDBM50645354 CHEMBL5575589

SMILES COc1ccc(Nc2ncnc3ccc(-c4c[nH]c5ncccc45)cc23)c(F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50645354   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645354(CHEMBL5575589)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of DYRK1A (unknown origin) preincubated with enzyme for 10 mins followed by substrate and ATP addition measured after 60 mins by ADP-Glo r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645354(CHEMBL5575589)
Affinity DataIC50: 48nMAssay Description:Inhibition of GSK-3beta (unknown origin) preincubated with enzyme for 10 mins followed by substrate and ATP addition measured after 60 mins by ADP-Gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50645354(CHEMBL5575589)
Affinity DataIC50: 55nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) preincubated with enzyme for 10 mins followed by substrate and ATP addition measured after 60 mins by A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed