BDBM50645402 CHEMBL5563407

SMILES Cc1c(Nc2c(F)ccc(NS(=O)(=O)C3CC3)c2Cl)ccc2ncn(C)c(=O)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50645402   

TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645402(CHEMBL5563407)
Affinity DataIC50: 141nMAssay Description:Inhibition of BRAF V600E mutant in human A-375 cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645402(CHEMBL5563407)
Affinity DataIC50: 250nMAssay Description:Inhibition of 6-His tagged BRAF V600E mutant (445 to 723 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed