BDBM50645436 CHEMBL5594973

SMILES C[C@@H](Nc1cc(N2CCN(C(N)=O)CC2)nc2nc(C3CC3)nn12)c1ccc2ccccc2c1

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50645436   

TargetP2X purinoceptor 3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50645436(CHEMBL5594973)
Affinity DataIC50: 55nMAssay Description:Antagonist activity at human P2X3R expressed in HEK293 cells incubated for 18 hrs by Fluo-4 dye based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetP2X purinoceptor 3(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50645436(CHEMBL5594973)
Affinity DataEC50:  362nMAssay Description:Antagonist activity at alpha, beta-meATP activated human P2X3 receptor by Fluo-4 dye based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50645436(CHEMBL5594973)
Affinity DataIC50: 1.18E+3nMAssay Description:Antagonist activity at human P2X2/3R expressed in HEK293 cells incubated for 18 hrs by Fluo-4 dye based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetP2X purinoceptor 1(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50645436(CHEMBL5594973)
Affinity DataIC50: 4.28E+3nMAssay Description:Antagonist activity at human P2X1 receptor expressed in 1321N1 cells incubated for 30 mins in presence of ATP by Fluo-4 dye based microplate reader a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetP2X purinoceptor 2(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50645436(CHEMBL5594973)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X2 receptor expressed in 1321N1 cells incubated for 30 mins in presence of ATP by Fluo-4 dye based microplate reader a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50645436(CHEMBL5594973)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X7 receptor expressed in 1321N1 cells incubated for 30 mins in presence of Bz-ATP by Fluo-4 dye based microplate reade...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetP2X purinoceptor 4(Human)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50645436(CHEMBL5594973)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X4 receptor expressed in 1321N1 cells incubated for 30 mins in presence of ATP by Fluo-4 dye based microplate reader a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed