BDBM50645461 CHEMBL5592950::US12527775, Compound I-102

SMILES CCCOc1ccc(CNC(=O)N(Cc2ccn(C)n2)[C@H]2CCN(C)CC23CC3)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50645461   

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50645461BDBM50645461(CHEMBL5592950 | US12527775, Compound I-102)
Affinity DataKi:  0.919nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/1/2026
Entry Details ArticleUS Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50645461BDBM50645461(CHEMBL5592950 | US12527775, Compound I-102)
Affinity DataKi:  0.940nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in Jump-In GripTite HEK293 cell membrane measured after 3 hrs incubation by sci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50645461BDBM50645461(CHEMBL5592950 | US12527775, Compound I-102)
Affinity DataKi:  4.01nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/1/2026
Entry Details ArticleUS Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 50645461BDBM50645461(CHEMBL5592950 | US12527775, Compound I-102)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2C receptor transfected in Jump-In GripTite HEK293 cell membrane measured after 3 hrs incubation by sci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed