BDBM50645654 CHEMBL5590420

SMILES COc1cccc(-c2cc(=O)c3ccccc3s2)c1N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50645654   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50645654(CHEMBL5590420)
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of RAF1- induced activation of MEK (unknown origin) signalling pathway assessed as reduction in MEK1 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50645654(CHEMBL5590420)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of RAF1- induced activation of MEK (unknown origin) signalling pathway assessed as reduction in ERK1/2 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed