BDBM50645757 CHEMBL5590255

SMILES c1cc(-c2coc3cc(-c4ccc(N5CCNCC5)cc4)cnc23)c2cccnc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50645757   

TargetActivin receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645757(CHEMBL5590255)
Affinity DataIC50: 130nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]ATP and 10 uM ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645757(CHEMBL5590255)
Affinity DataIC50: 134nMAssay Description:Inhibition of human ALK1 using casein as substrate in presence of [gamma-33P]ATP and 10 uM ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645757(CHEMBL5590255)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of human ALK6 using casein as substrate in presence of [gamma-33P]ATP and 10 uM ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645757(CHEMBL5590255)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ALK3 using casein as substrate in presence of [gamma-33P]ATP and 10 uM ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645757(CHEMBL5590255)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ALK5 using casein as substrate in presence of [gamma-33P]ATP and 10 uM ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645757(CHEMBL5590255)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ALK4 using casein as substrate in presence of [gamma-33P]ATP and 10 uM ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed