BDBM50645782 CHEMBL5303363

SMILES COc1cc(-c2cncc(-c3ccc(N4CCN(C(C)C)CC4)cc3)c2C)cc(F)c1C(=O)N1CCCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50645782   

TargetActivin receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645782(CHEMBL5303363)
Affinity DataEC50:  5.69E+3nMAssay Description:Inhibition of ALK2 NanoLuc fusion construct (unknown origin) incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645782(CHEMBL5303363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK1/2 in HEK293 cells transfected with CAGA response element luciferase based reporter assessed as inhibition of activin A-induced SMA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645782(CHEMBL5303363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK1/2 in HEK293 cells transfected with BMP response element luciferase based reporter assessed as inhibition of BMP7-induced SMAD-depe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645782(CHEMBL5303363)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ALK1 NanoLuc fusion construct (unknown origin) incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645782(CHEMBL5303363)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK1/2 in HEK293 cells transfected with CAGA response element luciferase based reporter assessed as inhibition of TGF beta1-induced SMA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645782(CHEMBL5303363)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ALK5 NanoLuc fusion construct (unknown origin) incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645782(CHEMBL5303363)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ALK3 NanoLuc fusion construct (unknown origin) incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645782(CHEMBL5303363)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ALK6 NanoLuc fusion construct (unknown origin) incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50645782(CHEMBL5303363)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ALK4 NanoLuc fusion construct (unknown origin) incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed