BDBM50645827 CHEMBL5595307

SMILES COC(=O)O[C@@H]1C(=O)C(C)=C2OC(=O)c3c(C)cc(O)c(C)c3O[C@@H]2[C@@]1(C)OC

InChI Key InChIKey=AAUDQADXJWOMJL-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50645827   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
LifeMine Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645827BDBM50645827(CHEMBL5595307)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of CDK2/Cyclin E1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50645827BDBM50645827(CHEMBL5595307)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
LifeMine Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645827BDBM50645827(CHEMBL5595307)
Affinity DataEC50:  6.50E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 NanoLuc fusion vector (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed