BDBM50645853 CHEMBL5593070

SMILES COc1cc(N)nc2cc(CN3C(=O)c4cc(F)ccc4[C@]34CCN(Cc3ccc(F)cc3)C4=O)[nH]c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50645853   

TargetProtein arginine N-methyltransferase 5(Human)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50645853(CHEMBL5593070)
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT5 in human HCT-116 cells with MTAP KO assessed as decrease in SMDA level incubated for 48 hrs by immunofluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed