BDBM50646062 CHEMBL5595838

SMILES Nc1nccc(Sc2cnc(N3CCC4(CC3)Cc3ncccc3[C@H]4N)cn2)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50646062   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Jacobio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50646062(CHEMBL5595838)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to SHP2 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Jacobio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50646062(CHEMBL5595838)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-NH2-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with enzyme for 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed