BDBM50646159 CHEMBL5592445::US12534451, Compound PZ-4060

SMILES CN(C)c1ccc(CC(=O)N2CCN(c3ccc(C#N)nn3)CC2)cc1

InChI Key InChIKey=WZGRSIMGJMUFMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50646159   

TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646159BDBM50646159(CHEMBL5592445 | US12534451, Compound PZ-4060)
Affinity DataIC50: 64nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPantothenate kinase 3(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646159BDBM50646159(CHEMBL5592445 | US12534451, Compound PZ-4060)
Affinity DataIC50: 64nMAssay Description:PANK activity assay was performed in the presence of 0-10 μM compound in a reaction mixture that contained 100 mM Tris-HCl, pH 7.5, 10 mM MgCl2, 2.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent