BDBM50646182 CHEMBL5589804

SMILES O=C(NO)[C@H](NS(=O)(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1)C1CCN(C(=O)c2ccccc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50646182   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 7(Homo sapiens)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50646182(CHEMBL5589804)
Affinity DataKi:  9nMAssay Description:Inhibition of recombinant human full-length ADAMTS7 truncated before the C-terminal PLAC domain using FAM-Glu-Ala-Ala-Ala-Arg-Ala-Glu-Ala-Ala-Ala-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 7(Homo sapiens)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50646182(CHEMBL5589804)
Affinity DataIC50: 50nMAssay Description:Inhibition of ADAMTS7 (unknown origin) proteolytic activity assessed as reduction in neoepitope antibody reactive fragment level using purified FLAG-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 7(Homo sapiens)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50646182(CHEMBL5589804)
Affinity DataIC50: 60nMAssay Description:Inhibition of ADAMTS7 (unknown origin) proteolytic activity assessed as increase in uncleaved LTBP4S-A level using purified FLAG-tagged LTBP4S-A as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed