BDBM50646232 CHEMBL5594904

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(=O)(O)O)cc1)NC(=O)CN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)O)C(C)C)[C@@H](C)O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50646232   

TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50646232(CHEMBL5594904)
Affinity DataKd:  150nMAssay Description:Binding affinity to STAT3 SH2 domain (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50646232(CHEMBL5594904)
Affinity DataIC50: 190nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50646232(CHEMBL5594904)
Affinity DataIC50: 220nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cedars-Sinai Medical Center

Curated by ChEMBL
LigandPNGBDBM50646232(CHEMBL5594904)
Affinity DataIC50: 290nMAssay Description:Displacement of 5-carboxyfluorescein GpYLPQTV-NH2 probe from C-terminal 6His-tagged recombinant human STAT3 (127 to 711 residues) SH2 domain extracte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed