BDBM50646535 CHEMBL5590363

SMILES CC(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](C)C(=O)C(=O)N[C@H](COCc1ccccc1)Cc1ccccc1)C(C)C

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50646535   

TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646535BDBM50646535(CHEMBL5590363)
Affinity DataKi:  1.40nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646535BDBM50646535(CHEMBL5590363)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Escherichia coli GlpG extracted from Escherichia coli C43(DE3) using KSp96 as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPresenilins-associated rhomboid-like protein, mitochondrial(Human)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646535BDBM50646535(CHEMBL5590363)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human PARL using KSp106 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRhomboid protease GlpG(Escherichia coli (strain K12))
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646535BDBM50646535(CHEMBL5590363)
Affinity DataEC50:  173nMAssay Description:Inhibition of GlpG in wild-type Escherichia coli MC4100 using MBP-Flag-LacYTMD2-Trx as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed