BDBM50646573 CHEMBL5590430

SMILES CN1CCCN(c2ccc(Nc3ncc(Br)c(Nc4ccccc4NS(=O)(=O)C4CC4)n3)cc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50646573   

TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646573(CHEMBL5590430)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of EGFR C797S/T790M/Del19 mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646573(CHEMBL5590430)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of EGFR C797S/T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646573(CHEMBL5590430)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646573(CHEMBL5590430)
Affinity DataIC50: 71nMAssay Description:Inhibition of wild-type EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed