BDBM50646648 CHEMBL5591160

SMILES Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-n1cc(-c2cncc(N3CCOCC3)c2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50646648   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50646648(CHEMBL5591160)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of RAF1 Y340D (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50646648(CHEMBL5591160)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of wild-type B-RAF (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50646648(CHEMBL5591160)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of B-RAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed