BDBM50646651 CHEMBL5593299

SMILES Cc1ccc(S(=O)(=O)NCCNc2nccc(-c3c(-c4cccc(F)c4)nc4occn34)n2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50646651   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50646651(CHEMBL5593299)
Affinity DataIC50: 34nMAssay Description:Inhibition of RAF1 (unknown origin) using MEK1 (K97R) as substrate preincubated for 30 mins followed by [gamma-33P]-ATP addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50646651(CHEMBL5593299)
Affinity DataIC50: 34nMAssay Description:Inhibition of C-RAF (unknown origin) by Hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed