BDBM50646707 CHEMBL5593832

SMILES COc1cc2c(NC3CCN(C(C)C)CC3)nc(C#N)nc2cc1OCCCN1CCOCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50646707   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 17nMAssay Description:Inhibition of NSD2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human NSD2 (941 to 1240 residues) using unmethylated histone H3 as substrate incubated for 40 mins in the presence of SAM a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 8.96E+3nMAssay Description:Inhibition of PRMT4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRMT8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MLL4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MLL1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50646707(CHEMBL5593832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed