BDBM50647265 CHEMBL5598106

SMILES COc1ccccc1N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50647265   

TargetSodium-dependent serotonin transporter(Human)
Shanghai Institute of Pharmaceutical Industry Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50647265(CHEMBL5598106)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in 5-HT reuptake incubated for 30 mins by fluorescent dye uptake assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Pharmaceutical Industry Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50647265(CHEMBL5598106)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human 5-HT1A receptor extracted from HEK293 cell membrane assessed as inhibition of [3H]-OH-DPAT binding to 5-HT1A by measuring i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Shanghai Institute of Pharmaceutical Industry Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50647265(CHEMBL5598106)
Affinity DataKi:  15nMAssay Description:Binding affinity to human 5-HT7 receptor extracted from HEK293 cell membrane assessed as inhibition of [3H]LSD binding to 5-HT7 by measuring inhibiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed